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Determinants of declining lung function trajectories from childhood to adulthood after preterm birth

Preterm birth is associated with lifelong respiratory sequelae, yet our understanding of lung function trajectories across the lifespan remains limited. We aimed to identify patterns of spirometry development from childhood to early adulthood in survivors of very preterm birth using novel data-driven methods.

Citation:
Gibbons JTD, Smith EF, Wilson AC, Simpson SJ. Determinants of declining lung function trajectories from childhood to adulthood after preterm birth. Thorax. 2026.

Keywords:
Bronchopulmonary Dysplasia; COPD Pathology; Paediatric Lung Disease; Pulmonary Disease, Chronic Obstructive

Abstract:
Preterm birth is associated with lifelong respiratory sequelae, yet our understanding of lung function trajectories across the lifespan remains limited. We aimed to identify patterns of spirometry development from childhood to early adulthood in survivors of very preterm birth using novel data-driven methods.