Reports and Findings
This report provides an update on the contemporary global and regional policy landscapes relevant to rheumatic heart disease
increased adherence to penicillin prophylaxis is associated with reduced acute rheumatic fever recurrence and a likely reduction in mortality
We propose that hydroxychloroquine could be repurposed to reduce the risk of rheumatic heart disease after acute rheumatic fever
Direct and indirect effects on pneumococcal carriage post-PCV10 are likely to result in reductions in pneumococcal disease, including in infants too young to be vaccinated
We analysed the stimulation of J8 antibodies in response to infection, and the role of existing J8 antibodies in protection against subsequent infection
A vaccine that prevents GAS cellulitis and other skin infections, in addition to throat infections, would maximise its value and commercial viability
Population-based primary prevention of ARF through sore throat management may be effective in well-resourced settings like New Zealand
Severe lower leg cellulitis presents a major burden to the health sector and is increasing with an ageing population
Severe lower leg cellulitis recurrences are frequent, and each episode increases the likelihood of subsequent recurrence and length of hospitalization
The authors present a variety of pressing clinical research questions on optimal RHD prevention and advanced care