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This study identified that expsoure to folate has effects on the regulation of DNA methylation during fetal development.

The complement system plays a major role in the autoimmune disease, systemic lupus erythematosus (SLE). This review highlights the many roles of complement for

The Pregnancy and Early Life Immunology team's overall research vision is targeted towards understanding immunological development during early life.

This study aims to investigate the cellular and molecular profiles of the immune system in infants at high/low risk for Autism, as determined through clinical assessment.

We are studying immune cells from identical twins of which one suffers and one does not suffer from allergic disease to identify specific mechanisms that may play important roles in disease development.

This study is designed to identify the specific unique immune cell response that occurs in these children with recurrent disease.

Studies in Europe show exposure of pregnant women to high levels of microbial products stimulate immune function maturation in their offspring

The study aims to identify the mechanism for this so that this knowledge can be used to better treat asthma and allergies in both males and females.

This project investigates how cells of the immune system respond to substances to cause allergies to help develop new treatments.

Nontypeable Haemophilus influenzae (NTHi) is a major otitis media (OM) pathogen, with colonization a prerequisite for disease development. Most acute OM is in children <5 years old, with recurrent and chronic OM impacting hearing and learning. Therapies to prevent NTHi colonization and/or disease are needed, especially for young children. Respiratory viruses are implicated in driving the development of bacterial OM in children.