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This review article examines the evidence of the impact of in utero and postnatal vitamin D exposure on allergy risk in childhood

This article focuses on IgE-mediated food allergies and allergic rhinitis, the most commonly seen conditions in paediatric immunology.

Reliance on increasing use of dietary supplementation and fortification (eg, with folate) to compensate for increased consumption of processed foods is also...

This study identified that expsoure to folate has effects on the regulation of DNA methylation during fetal development.

This paper is a review about the importance of alterations to the DNA molecule, rather than the DNA sequence, in the development of the immune system, and...

Vitamin D status in early life has been linked to the risk of allergic disease in multiple observational studies.

The proposal that dietary docosahexaenoic acid (DHA) enhances neurocognitive functioning in term infants is controversial.

With more than one in four Australian children overweight or obese, and the significant risks this poses for health problems like asthma, depression,...

Reasons for Th2 skewing in IgE-mediated food allergies remains unclear. Clinical observations suggest impaired T cell activation may drive Th2 responses evidenced by increased atopic manifestations in liver transplant patients on tacrolimus (a calcineurin inhibitor). We aimed to assess differentiation potential, T cell activation and calcium influx of naïve CD4+ T cells in children with IgE-mediated food allergies. 

Infant growth trajectories reflect current health status and may predict future obesity and metabolic diseases. Human milk is tailored to support optimal infant growth. However, nutrient intake rather than milk composition more accurately predicts growth outcomes. Although the role of protein leverage in infant growth is unclear, protein intake is important for early infancy growth.