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People born preterm (<37 weeks’ gestation) have lower peak oxygen consumption (peak VO2), a well-established indicator of long-term health outcomes, compared to term-born peers. However, responses to exercise can vary with exercise mode, which has implications for prognostic assessments.
Limited evidence suggests that airway epithelial structure and function is disrupted in very preterm infants; however, the epithelial morphology and physiology has not been well characterised following discharge from neonatal intensive care. This study aimed to characterise the nasal airway epithelium from 1-year-old survivors of very preterm birth.
Preterm birth and subsequent neonatal ventilatory treatment disrupts development of the hypoxic ventilatory response (HVR). An attenuated HVR has been identified in preterm neonates, however it is unknown whether the attenuation persists into the second year of life.
This is the largest collection of normative T LCO data, and the first global reference values available for T LCO.
The lung clearance index may be a useful surveillance tool for monitoring the presence and extent of lower airway inflammation and infection
To obtain comprehensive data on lung structure and function in mid-childhood from survivors of preterm birth.
This review summarizes what we have learned about early lung disease in children with CF and discusses the implications for clinical practice and research
We aimed to quantify the diagnostic utility of mannitol challenge testing for asthma in a community cohort and a symptomatic wheezing subset of this cohort.
To assess the determinants of early lung function in African infants.
The significance of both indoor and outdoor sources of air pollution and effect modifiers such as green space and heating require further investigation