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Whole genome sequencing of poor and exceptional survivors identified a gain in Chromosome 19 that was exclusive to the exceptional survivors

These findings reveal a central role of the DG receptor, not only as a structural element, but also as a critical factor promoting mesenchymal-like GBM

Our current Research Topic highlights the complexity of the relationship between the skin, immune system and skin cancer

Our results identify a pretreatment tumor microenvironment that predicts response to immune checkpoint blockade, which can be therapeutically attained

These findings suggest that tumor cells employ multiple epigenetic and genetic mechanisms to evade immune control

Our findings provide insight into the immune cell populations important for maintaining long-term tumour dormancy in peripheral tissues

In this review, we discuss the different subsets of tumor-infiltrating dendritic cells and their role in anti-tumor immunity

Our data demonstrate that CD8+XCR1neg DCs possess a unique pattern of endocytic receptors and a restricted TLR profile that is particularly enriched for TLR5

Our results show that TRM cells have a fundamental role in the surveillance of subclinical melanomas in the skin by maintaining cancer-immune equilibrium

Our findings present a novel mouse model for glioma demonstrating that the PI3K pathway is important for initiation of tumorigenesis