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Early respiratory viral infections in infants with cystic fibrosis. Abstract Background: Viral infections contribute to morbidity in cystic fibrosis
Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability. Rationale: No studies
Airway surface liquid pH is not acidic in children with cystic fibrosis Modulation of airway surface liquid (ASL) pH has been proposed as a therapy
Conditionally reprogrammed primary airway epithelial cells maintain morphology, lineage and disease specific functional characteristics The study of
Parental Experience of Information and Education Processes Following Diagnosis of Their Infant With Cystic Fibrosis Via Newborn Screening. Abstract
The clinical significance of oropharyngeal cultures in young children with cystic fibrosis ABSTRACT In children with cystic fibrosis (CF) the
Research
BAL Inflammatory Markers Can Predict Pulmonary Exacerbations in Children With Cystic FibrosisPulmonary exacerbations in cystic fibrosis are characterized by airway inflammation and may cause irreversible lung damage. Early identification of such exacerbations may facilitate early initiation of treatment, thereby potentially reducing long-term morbidity. Research question: Is it possible to predict pulmonary exacerbations in children with cystic fibrosis, using inflammatory markers obtained from BAL fluid?
We tested the hypothesis that treatment of CF epithelial cells with ivacaftor (Iva) or ivacaftor/lumacaftor (Iva/Lum) would improve control of rhinovirus infection.
Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis. Abstract Although destructive airway
Assessment of early lung disease in young children with CF: A comparison between pressure-controlled and free-breathing chest computed tomography