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Early respiratory viral infections in infants with cystic fibrosis.

Early respiratory viral infections in infants with cystic fibrosis. Abstract Background: Viral infections contribute to morbidity in cystic fibrosis

Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability.

Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability. Rationale: No studies

Airway surface liquid pH is not acidic in children with cystic fibrosis

Airway surface liquid pH is not acidic in children with cystic fibrosis Modulation of airway surface liquid (ASL) pH has been proposed as a therapy

Conditionally reprogrammed primary airway epithelial cells maintain morphology, lineage and disease specific functional characteristics

Conditionally reprogrammed primary airway epithelial cells maintain morphology, lineage and disease specific functional characteristics The study of

Parental Experience of Information and Education Processes Following Diagnosis of Their Infant With Cystic Fibrosis Via Newborn Screening.

Parental Experience of Information and Education Processes Following Diagnosis of Their Infant With Cystic Fibrosis Via Newborn Screening. Abstract

The clinical significance of oropharyngeal cultures in young children with cystic fibrosis

The clinical significance of oropharyngeal cultures in young children with cystic fibrosis ABSTRACT In children with cystic fibrosis (CF) the

Research

BAL Inflammatory Markers Can Predict Pulmonary Exacerbations in Children With Cystic Fibrosis

Pulmonary exacerbations in cystic fibrosis are characterized by airway inflammation and may cause irreversible lung damage. Early identification of such exacerbations may facilitate early initiation of treatment, thereby potentially reducing long-term morbidity. Research question: Is it possible to predict pulmonary exacerbations in children with cystic fibrosis, using inflammatory markers obtained from BAL fluid?

Ivacaftor or lumacaftor/ivacaftor treatment does not alter the core CF airway epithelial gene response to rhinovirus

We tested the hypothesis that treatment of CF epithelial cells with ivacaftor (Iva) or ivacaftor/lumacaftor (Iva/Lum) would improve control of rhinovirus infection.

Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis.

Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis. Abstract Although destructive airway

Assessment of early lung disease in young children with CF: A comparison between pressure-controlled and free-breathing chest computed tomography

Assessment of early lung disease in young children with CF: A comparison between pressure-controlled and free-breathing chest computed tomography