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Science of the swab: optimising Strep A typing from clinical samples
Asha Dylan Janessa Tim Bowen Barth Pickering Barnett BA MBBS DCH FRACP PhD GAICD FAHMS OAM B.Tech, MPH, PhD BSc PhD PhD Head, Healthy Skin and ARF
Tonsil organ model to evaluate carriage, disease mechanisms and therapeutic interventions for treatment and prevention of GAS infections
Tonsil organ model to evaluate carriage, disease mechanisms and therapeutic interventions for treatment and prevention of Group A Streptococcal infections.
Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP
Our results suggest that intracellular infection with the pathogenic GAS M1T1 clone induces a strong pro-inflammatory response in primary tonsil epithelial cells
Group A streptococcal pharyngitis: Immune responses involved in bacterial clearance and GAS-associated immunopathologies
Innate and adaptive host immune responses are fundamental for defense against streptococcal pharyngitis and are central to the clinical manifestation of disease.