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News & Events
Flu study gives vital early protection to bubs this winterThe FluBub Study will investigate whether giving the flu vaccine much earlier than the six months currently recommended by the National Immunisation Program will protect babies at the greatest risk of a severe influenza infection when they are most vulnerable.
News & Events
The Kids Research Institute Australia launches Covid-19 booster research to inform Australia’s vaccine policyOptimising our national Covid-19 vaccine program could be one step closer thanks to new research now underway at The Kids Research Institute Australia investigating the most effective, long-term strategies for booster vaccinations.
News & Events
New Aboriginal Cultural Guidance Advisor appointedThe Wesfarmers Centre of Vaccines and Infectious Diseases has appointed Mrs Valerie Swift to a newly created Aboriginal Cultural Guidance Advisor position.
News & Events
Round one done, eight to go for the SToP TrialSix weeks, nine community visits and 380 kids – it’s a wrap for round one of the StoP Trial!
News & Events
Early ear infections linked to higher risk of future problems: studyResearchers have found kids who experience repeat ear infections in infancy have a much higher risk of ongoing problems with ear infections in later childhood
Research
Nasal Delivery of Haemophilus haemolyticus Is Safe, Reduces Influenza Severity, and Prevents Development of Otitis Media in MiceDespite vaccination, influenza and otitis media (OM) remain leading causes of illness. We previously found that the human respiratory commensal Haemophilus haemolyticus prevents bacterial infection in vitro and that the related murine commensal Muribacter muris delays OM development in mice. The observation that M muris pretreatment reduced lung influenza titer and inflammation suggests that these bacteria could be exploited for protection against influenza/OM.
Research
Serological Responses to Streptococcus pyogenes Vaccine Candidate Antigens Suggests That Streptococcus dysgalactiae Is the Predominant Cause of Lower Limb CellulitisA future Streptococcus pyogenes (Strep A) vaccine will ideally prevent a significant burden of lower limb cellulitis; however, natural immune responses to proposed vaccine antigens following an episode of cellulitis remain uncharacterized.
Research
Bringing optimised COVID-19 vaccine schedules to immunocompromised populations (BOOST-IC): study protocol for an adaptive randomised controlled clinical trialImmunocompromised hosts experience more breakthrough infections and worse clinical outcomes following infection with COVID-19 than immunocompetent people. Prophylactic monoclonal antibody therapies can be challenging to access, and escape variants emerge rapidly. Immunity conferred through vaccination remains a central prevention strategy for COVID-19.
Research
DNA Methylation signatures underpinning blood neutrophil to lymphocyte ratio during first week of human lifeUnderstanding of newborn immune ontogeny in the first week of life will enable age-appropriate strategies for safeguarding vulnerable newborns against infectious diseases. Here we conducted an observational study exploring the immunological profile of infants longitudinally throughout their first week of life.
Research
Antecedent and persistent symptoms in COVID-19 and other respiratory illnesses: Insights from prospectively collected data in the BRACE trialSome individuals have a persistence of symptoms following both COVID-19 (post-acute COVID-19 syndrome; PACS) and other viral infections. This study used prospectively collected data from an international trial to compare symptoms following COVID-19 and non-COVID-19 respiratory illness, to identify factors associated with the risk of PACS, and to explore symptom patterns before and after COVID-19 and non-COVID-19 respiratory illnesses.