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Research

A novel technique of serial biopsy in mouse brain tumour models

Here we describe a method by which serial biopsy can be used to validate response to dacomitinib treatment in vivo using a mouse glioblastoma model

Research

Group A Streptococcus, Acute Rheumatic Fever and Rheumatic Heart Disease: Epidemiology and Clinical Considerations

A directed approach to the differential diagnosis of acute rheumatic fever now includes the concept of low-risk versus medium-to-high risk populations

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Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsin

Identified romidepsin as a promising therapeutic for mixed lineage leukemia (MLL)-rearranged infant acute lymphoblastic leukemia

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Evidence of a reduction over time in the behavioral severity of autistic disorder diagnoses

This study provides the first clear evidence of a reduction over time in the behavioral severity of individuals diagnosed with Autistic Disorder during a period of stability in diagnostic criteria

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Childhood atopy and mental health: a prospective, longitudinal investigation

Findings are the first linking atopy (measured by both parent report and objective verification) with increased vulnerability to affective and anxiety problems

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Nowhere to Go and Nothing to Do but Sit? Youth Screen Time and the Association With Access to Neighborhood Destinations

With not much to do in their neighborhood, youth may spend more time in the home engaged in screen-based activities

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Congenital Cytomegalovirus among Children with Cerebral Palsy

To determine the proportion of children with CP and CMV, taking various factors into account.

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The effect of 100% oxygen on tidal breathing parameters in preschool children

This study aimed to determine whether breathing 100% oxygen altered tidal breathing parameters in healthy young children and young children with CF.

Research

#Parentingtips: A Descriptive Study of Information for Parents on TikTok

Parents and caregivers often turn to the internet for information about their child's health and development. Research investigating content related to parenting on the world's most popular social media platform, TikTok, has not been conducted.

Research

Co-occurring Neurodevelopmental Conditions in Children: Advocating for Transdiagnostic Approach to Assessments

Approximately 8% of all children experience developmental and mental health conditions. Similarities in characteristics across neurodevelopmental conditions-such as difficulties in communication and language, social interaction, motor coordination, attention, activity regulation, behavior, mood, and sleep-make it challenging to attribute these characteristics exclusively to specific diagnoses and assessments. The purpose of this study was to identify symptomatic domains across neurodevelopmental conditions in children and to explore dimension reduction for transdiagnostic assessment.