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Chronic innocuous aeroallergen exposure attenuates CD4+ T cell-mediated airways hyperresponsiveness in mice; however, the mechanism(s) remain unclear
Airway epithelial cells act through multiple mechanisms to function as an important component of the pulmonary defence strategy that is crucial...
Atopic asthma, which is at its highest prevalence during childhood/young adulthood, represents the main focus of this review.
Airways hyperresponsiveness (AHR) is one of the major clinical features of allergic airways disease including allergic asthma
We have recently published a paper identifying precursor populations in peripheral lung (2017), and have also discovered that these populations can be found in multiple tissues.
This study will identify how the immune system contributes to neurodevelopmental outcomes and will investigate the use of an agent from traditional medicines.
This study will investigate the why disease is worse in infants and how early life viral infection impacts the developing immune system.
This is a strategic “pilot” project in which we are seeking basic information on the immune cell content of gestational tissues.
This project investigates how different populations of cells within the respiratory tract immune system are altered during a viral infection.
Head, Pregnancy and Early Life Immunology