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Partial trisomy 21 contributes to T-cell malignancies induced by JAK3-activating mutations in murine modelsThis JAK3A572V knockin model is a relevant new tool for testing the efficacy of JAK inhibitors in JAK3-related hematopoietic malignancies
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Using linked data to investigate developmental vulnerabilities in children of convicted parentsAlthough children of convicted parents experience a higher incidence of sociodemographic risk, their parents' criminal activity constitutes an independent risk factor for their development
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Systemic antibiotics for chronic suppurative otitis mediaTo assess the effects of systemic antibiotics for people with chronic suppurative otitis media.
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Topical antiseptics for chronic suppurative otitis mediaTo assess the effects of topical antiseptics for people with chronic suppurative otitis media
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How New and Expecting Fathers Engage With an App-Based Online Forum: Qualitative AnalysisThese data show that fathers are prepared to use a breastfeeding-focused online forum in a variety of ways to facilitate social support
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Evaluation of a public education campaign to support parents to reduce adolescent alcohol useThe Parents, Young People and Alcohol campaign achieved high awareness and positively influenced parental outcomes
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Preterm birth: Born too soon for the developing airway epitheliumThis review examines the consequences of preterm birth on the airway epithelium and explores the clinical relevance of currently available models
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Antibiotic appropriateness and guideline adherence in hospitalized children: results of a nationwide studyInappropriate antimicrobial prescribing in children was linked to specific risk factors, presenting opportunities for targeted interventions to improve prescribing
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Outcome of Infants Younger Than 1 Year With Acute Lymphoblastic Leukemia Treated With the Interfant-06 Protocol: Results From an International Phase III Randomized StudyEarly intensification with postinduction myeloid-type chemotherapy courses did not significantly improve outcome for infant acute lymphoblastic leukemia
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A Novel Missense Mutation Affecting the N-terminal Domain of SAP Protein in X-linked Lymphoproliferative DiseaseWe have revealed a novel SH2D1A gene mutation in a patient with XLP resulting in fulminant refractory EBV-driven HLH, which is a recognized severe complication